ABSTRACT
INTRODUCTION: The COVID-19 pandemic influences the spirituality and mental health of individuals. It also has caused a global economic recession. COVID-19 is easily transmitted and causes death. Consequently, severe prevention and control measures of COVID 19 are required in this situation. This study aims to analyze the relationship between anxiety, stigma, religiosity, economic conditions, and the prevention of COVID-19. METHODOLOGY: A cross-sectional study was designed. The data collection was taken through online surveys. The population in this study is ninety-two lecturers from the College of Health Sciences and the State Islamic Institute who were chosen using a non-probability snowball sampling technique. Data analysis used logistic regression analysis. RESULTS: The results showed that there was a relationship between anxiety (p = 0.001), stigma (p = 0.008), religiosity (p = 0.005) and the efforts to prevent COVID-19, while economic conditions (p = 0.882) were not related to the preventive efforts. The results of multivariate analysis indicated that the most influential variable affecting COVID-19 preventions was the level of anxiety, with an Odds Ratio of 4.9. CONCLUSIONS: There was a relationship between anxiety, stigma, religiosity, and COVID-19 preventions, while there was no relationship between economic conditions and COVID-19 preventions. The most influencing variable was anxiety. Respondents must be able to manage anxiety levels related to COVID-19 with good coping strategies.